Forscher haben eine Proof-of-Concept-Studie veröffentlicht, die zeigt, dass injizierbares Semaglutid für Frauen mit polyendokrinem metabolischem Ovarialsyndrom (PMOS), früher bekannt als PCOS, bedeutende reproduktive Vorteile bieten kann
https://news.cuanschutz.edu/news-stories/injectable-semaglutide-shows-early-promise-to-improve-fertility-in-women-with-pmos?utm_campaign=semaglutide&utm_source=reddit&utm_medium=social
14 Kommentare
I’m so glad we’re moving beyond telling people with PCOS to just lose weight as if the weight isn’t a symptom of PCOS, and instead getting them treatment that can reverse PCOS to stop the metabolic cascade it causes.
God, finally. A little spark of hope after being told to just take BC for years.
The glp1 subs are full of women who were told they were infertile and got pregnant on these drugs.
Lilly is keeping a registry to track the pregnancies.
As a 42f without PMOS who’s tracked their period for more than 3 decades, my menstrual cycle completely changed when I started a tirzepitide.
My wife and I did IVF for our first. She got on GLP-1s and we were pregnant her 1st month off birth control
I thought getting pregnant on GLP-1 drugs was counter indicated?
Anecdotal, but I have PMOS and struggled with infertility for 5 years (had 3 miscarriages). I got pregnant 6 months after being on wegovy and now have a happy, healthy 10 month old.
Damn for real? Maybe I can finally treat my PMOS properly
This sub has become PR for the pharmaceutical industry.
I (39F) was going through a stressful time in life where I was contemplating a career change. Prior to that throughout my 30s, I had been slowly gaining weight while still training for half marathons or smaller races, lifting weights, and doing aerials. I had worked with two PMOS registered dietitians and still no weight loss. I got to the point where I was considered obese on BMI and a PMOS registered dietitian was offering her group coaching program and had an offer with Heally, an online compounding pharmacy. I registered for her program and used Heally to get tirzepatide. I lost 30ish pounds and have kept the weight off for over a year. I can only describe it as weight loss was actually fair. I stick to what I’ve learned nutrition wise with her group coaching program and really focused on Peloton strength training while I was taking tirzepatide. My cycle, which was so whack a doodle and never came on time, came and still comes like clockwork every 35 days. I had tried metformin and birth control with no luck whatsoever. This stuff is a miracle and I wish I could’ve stayed on a low dose, hoping it’s approved for PMOS someday!
And yet it still isn’t covered for people with PMOS. $500 a month, every month
I wrote an entire post-grad paper on the use of GLP-1 in PCOS. The assignment exercise was mostly to show that we understand how to read and interpret RCTs and find good evidence to use something in practice. Unfortunately there weren’t a bunch of well designed RCTs comparing the same exact drug but even with comparing different GLP-1 medications the research is great. I hope more and more research comes out because I’m very keen to apply for government funding of GLP-1s for use in obese women with PCOS. they’re incredible for so many of the metabolic/endocrine symptoms!
For women with pmos who got pregnant on these drugs, how long did you wait to conceive after getting off them?
Sure, but does it help with the debilitating menstrual pain from PMOS?
Not surprised, it completely eliminated my endometriosis pain/inflammation. To the point I forget I’m on the list for a total hysterectomy and wondering if I ask for a new exam to see if I can just get away with an oophringotomy