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    Der gemeinsame Konsum von Cannabis und Tabak erhöht das Risiko, psychotische Störungen wie Schizophrenie zu entwickeln, bei Personen, die als Hochrisikogruppe gelten, um das Dreifache

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    1. sr_local on

      >The study found that regular use of either cannabis or tobacco was linked to anxiety, depression and early psychotic experiences. However, people who used cannabis and tobacco together did not show worse short-term symptoms than those using just one.  
      >
      >However, the biggest difference appeared over time. Those who used cannabis heavily and tobacco lightly were almost three times more likely to develop psychosis compared to those who used neither substance.  
      >
      >The results highlight concern about co-use, a growing trend that has been understudied until now. Researchers defined co-use in the study as “using substances at the same time, on the same occasion, or within a defined time frame where their effects may overlap.”  
      >
      >“We found that cannabis and tobacco co-use was associated with a nearly threefold increased risk of developing psychosis in people who were already at risk,” Ward said. “There is evidence to suggest that using tobacco and cannabis together may have synergistic effects on the brain.  
      >
      >“Smoking tobacco and cannabis together increases absorption of THC, the psychoactive component of cannabis. It is possible that co-use itself is contributing to the development of psychosis. However, it is also possible that the people who are going to develop psychosis anyway have an underlying predisposition to using both cannabis and tobacco.”  

      [Cannabis and tobacco co-use predicts psychosis in clinical high risk cohorts | Nature Mental Health](https://www.nature.com/articles/s44220-026-00648-y)

    3. HairyNutsack69 on

      Nicotine or tobacco? 

      Id wager a guess it’s nicotine because snus+weed does the same thing as a spliff for me

      Edit: „A major limitation
      is that the data were collected from 2009 to 2013, before the legalization of recreational cannabis use, the emergence of vaping (nicotine
      and THC)49,50 and other noncombustible nicotine use“

      They ain’t know

    6. OkPhilosopher5626 on

      Could it have to do with nicotine dependance and cross association with weed?

      Eg someone starting to smoke weed straight vs mixing with tobacco – the person mixing with tobacco may take in less weed per joint, but may associate thv with the nicotine reward centre – particularly if they don’t usually smoke tobacco otherwise.

      I would imagine that the cravings will be more intense for the mixer, and they may get conditioned to relieving the nicotine cravings and smoking more regularly or developing a stickier dependance pattern.

    8. Icy-Elk3698 on

      Correlation does not mean causation. I’d be more inclined to believe that people with eventual schizophrenia were more likely self medicating to quiet their symptoms and/or trauma rather than the combination of weed and tobacco causing a psychotic break.

    13. MadroxKran on

      I’ve seen a few articles like this, but then why don’t we see any noticeable uptick in psychotic disorders in countries that legalized marijuana long ago?

    14. arthurdentstowels on

      What about doing the exact same thing but cleaner? I use a dry herb vape plus I also use a nicotine vape. Is this the same situation or is it down to all of the other chemicals released when burning the weed and tobacco?

    15. CantaloupeAsleep502 on

      Does it increase the risk, or are people who will develop schizophrenia also more inclined to use those substances?

    16. PM_ME_UR_MUNCHIES on

      It was how we were taught to consume the dang stuff… if we had been taught to take it without tobacco for health reasons probably would have listened

    17. Liminitial on

      >However, it is also possible that the people who are going to develop psychosis anyway have an underlying predisposition to using both cannabis and tobacco

      This was my question. This seems more correlative than causative.

    20. colacolette on

      From this article: „However, it is also possible that the people who are going to develop psychosis anyway have an underlying predisposition to using both cannabis and tobacco.” i am studying in this same field and it is proving immensely challenging to disentangle whether cannabis is causal for psychosis development. Which is obviously important for us to know-it would make it a much higher-risk drug for at risk adolescents than it is currently viewed as.

    22. truebeast822 on

      “Smoking tobacco and cannabis together increases absorption of THC” well that being said, hook it up

    26. ino4x4 on

      when it comes to anything I put on my brain always do one at a time. Mixing things is how you go crazy. People do both of those things and drink alcohol. I don’t get it.

    28. nicknaksowhack on

      “Among those considered high risk” so if you’re already at risk, they put you further at risk. What if you’re not high risk?

    31. WorkflowBuilder_ on

      People, take care of both your mental and physical health! If you can (which I’m sure you can) do not engage yourself with this kind of addiction.

    32. Same-Platypus1941 on

      Cannabis and cigarettes, smoked one after the other, has been my drug of choice for my entire adult life. I struggle with manic psychosis and have been diagnosed with bipolar 1 as an adult. I know my anecdotal experience doesn’t mean much but I find it worth noting given how on point it is with the study.

    33. Apart-District3771 on

      Maybe, just maybe, those types of people are drawn to mind altering substances…

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