Eine geringe Dosis Antibiotika führt zu guten Ergebnissen bei der Behandlung von Panikattacken. Eine Studie mit Tieren und Menschen zeigte, dass Minocyclin in niedrigeren Dosen als bei bakteriellen Infektionen eine entzündungshemmende Wirkung auf Mikroglia hat, das sind Gehirnzellen, die sich bei Menschen mit dieser Erkrankung stärker entzünden.
https://agencia.fapesp.br/small-dose-of-antibiotic-yields-good-results-in-treating-panic-attacks/57917
23 Kommentare
Small dose of antibiotic yields good results in treating panic attacks
A study involving animals and humans showed that minocycline, in doses lower than those administered for bacterial infections, has an anti-inflammatory effect on microglia, which are brain cells that become more inflamed in people with the disorder.
A study supported by FAPESP shows that small doses of the antibiotic minocycline may help treat panic disorder. Experiments conducted at São Paulo State University (UNESP) in mice and at the Federal University of Rio de Janeiro (UFRJ) in humans showed that minocycline has a similar effect to clonazepam, the most commonly prescribed anti-panic medication and best known by its brand name, Rivotril.
The study was published in the journal Translational Psychiatry.
The antibiotic doses required to treat panic attacks in the study were lower than those used to treat bacterial infections, reducing the likelihood of developing bacterial resistance.
https://www.nature.com/articles/s41398-026-03836-7
Reducing but not eliminating the chances of making a problem that already exists worse, nice.
Other things also work for panic attacks that require no risk of anything like that.
This is really interesting. There’s some evidence that depression and anxiety can be related to brain inflammation, especially those resistant to medication. Pathogenic microbes can be a driver of this, so it’s really interesting to see a benefit in using antibiotic to reduce inflammation with good relief.
Even ibuprofen helps me with panic and anxiety when it comes up from time to time. I also noticed feeling better mentally after being sick with the flu/a cold and taking meds and sleeping. The anxiety would gradually return as I got back to normal after getting over the illness.
Inflammation really seems to be the uber culprit in human health disorders.
Tetracyclines like minocycline and doxycycline have long been known for anti-inflammatory properties. The neuroprotective effect of minocycline has been known for at least 20 years.
Let’s create the ultimate bacteria, extinction speed run.
Anything but just giving poor people a Xanax or Ativan when they’re suffering.
Meanwhile rich soccer moms have whole candy dishes full of klonopin throughout their house.
Had a patient swear that a z-pack cured his insomnia. I laughed. Now I’m wondering…
Anyone who’s smarter than me answer a question I had about this? I know you’re not supposed to stop antibiotics early, because of antibiotic resistance— but would this small amount be a problem if someone was on this regime and also got a bacterial infection? Would you need to stop the antibiotics or take a stronger amount..? I’m just curious because this is fascinating.
I got long COVID 5 years ago and still battle with it daily.
Part of my long list of symptoms include brain problems. I believe neuro inflammation is at play.
Very curious if this would help…
Oh god this study is very productive but the headline is awful, people’s use of antibiotics is already problematic as it is.
Are these the same antibiotics that wreck your GI biome and damage your long term health?
I was chronically sick as a child, I was never more at ease as when I was sick and on the mend with frequent antibiotics. I just assumed it was not going to school but…
Just an FYI. Something must have been lost in the translation.
This is talking about treating anxiety disorder. NOT acute panic attacks.
Minocycline gave me drug-induced lupis, which is an autoimmune disorder characterized by inflamed/swollen and painful joints. I was taking it for acne at the time. It’s incredible the difference a dosage level makes (one causes inflammation, one reduces).
I only time I had severe panic attacks was when I was in tick country. I’d found ticks on my pants but couldn’t find any bite marks. But it was a day or two later that I had a full blown panic attack. Just absolute terror for no obvious reason, and then once again about two weeks later. I knew there was no objective reason to be so scared, and the only slightly comforting response was to curl up into a ball under my bed covers.
This is a great opportunity to treat neuro inflammation. we just need a better way to measure it.
I wonder if its a related mechanism to the one that gives people „an impending sense of doom“ when they get the wrong blood transfusion.
Ah yes, the answer we’ve been waiting for, to the question we shouldn’t have been asking:
> How can we best incentivise and accelerate the development of antibiotic resistant bacteria?
I didn’t read the article but the title brought me. I was on minocycline for acne long term and actually developed autoimmune hepatitis that went away after 5-6 years of treatment.
I have a autoimmune disorder that causes my immune system to be way over active. I also have horrible anxiety. I never actually thought about the two being related.
Prob get the same effect from drinking a couple of beers