Wissenschaftler entdecken „bakterielle Verstopfung“, eine neue Krankheit, die durch Darmbakterien verursacht wird. Akkermansia muciniphila und Bacteroides thetaiotaomicron zerstören die Schleimschicht im Darm, die für die Befeuchtung des Dickdarms und die Hydratation des Kots unerlässlich ist. Übermäßiger Abbau führt bei Patienten zu trockenem, unbeweglichem Stuhl.

**Scientists discover “bacterial constipation,” a new disease caused by gut-drying bacteria**

Two bacteria working together to break down intestinal mucus are identified as a contributing factor to chronic constipation

Scientists at Nagoya University in Japan have found two gut bacteria working together that contribute to chronic constipation. **The duo, Akkermansia muciniphila and Bacteroides thetaiotaomicron, destroy the intestinal mucus coating essential for keeping the colon lubricated and feces hydrated. Their excess degradation leaves patients with dry, immobile stool**. This discovery, published in Gut Microbes, finally explains why standard treatments often fail for millions of people with chronic constipation.

Notably, the study shows that Parkinson’s disease patients, who suffer from constipation decades before developing tremors, have higher levels of these mucus-degrading bacteria. While constipation in Parkinson’s disease has traditionally been attributed to nerve degradation, these findings suggest that bacterial activity also plays a crucial role in the development of their symptoms.

For those interested, here’s the link to the peer reviewed journal article:

https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2596809