Niedrig dosiertes Psilocybin reduziert Gewichtszunahme und Hyperglykämie bei Mäusen, die mit adipöser Diät gefüttert wurden. Die Ergebnisse zeigten, dass Mäuse, die Psilocybin erhielten, im Vergleich zur Kontrollgruppe eine geringere Gewichtszunahme, Lebersteatose, Hyperglykämie und Insulinresistenz aufwiesen.

>A study of mice fed a high-fat/high-fructose diet (designed to induce obesity) found that 12 weeks of treatment with low-dose psilocybin reduced weight gain, symptoms of fatty liver, hyperglycemia, and insulin resistance. It did not produce observable effects on the central nervous system. The [paper](https://doi.org/10.1016/j.phrs.2025.108080) was published in Pharmacological Research.

>Psilocybin is a naturally occurring psychedelic compound found in certain species of mushrooms, often referred to as “magic mushrooms.” In the body, psilocybin is converted into psilocin, which affects brain function by acting primarily on serotonin (5-HT2A) receptors. These effects can alter perception, mood, cognition, and sense of self. Subjective experiences may include changes in visual perception, intensified emotions, and altered patterns of thought.

>Historically, psilocybin-containing mushrooms have been used in ritual and spiritual practices in several cultures. In contemporary science, psilocybin has gained attention for its potential therapeutic effects. Clinical research suggests it may reduce symptoms of depression, anxiety, and existential distress, particularly in controlled, supportive settings.

>Psilocybin-assisted therapy typically combines the drug with psychological preparation and integration sessions. The compound is generally considered to have low addiction potential, though its effects can be psychologically intense. Legal status varies widely across countries, with some allowing medical or research use and others maintaining strict prohibitions.

I’ve been saying for years that they will help you live longer, happier, and healthier.