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    Alkoholkonsum steht bei über 400.000 US-Veteranen im Zusammenhang mit Herzversagen. Das Risiko folgt einem J-förmigen Muster im Zusammenhang mit der Ethanolaufnahme und steigt über vier Getränke pro Tag an.


    Alkoholkonsum steht bei über 400.000 US-Veteranen im Zusammenhang mit Herzversagen. Das Risiko folgt einem J-förmigen Muster im Zusammenhang mit der Ethanolaufnahme und steigt über vier Getränke pro Tag an.

    https://www.mdpi.com/2072-6643/18/3/471

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    1. sometimeshiny on

      ### [Alcohol Intake and Incidence of Heart Failure and Its Subtypes: VA Million Veteran Program (2026) – Nguyen et al.](https://doi.org/10.3390/nu18030471)

      | Abstract |
      |—|
      | Background: Little is known about the relation between total alcohol intake and beverage types with the risk of heart failure (HF) and its subtypes in the veteran population. This study aims to examine the associations between total and type of alcohol consumption and risk of HF and its subtypes, namely HF with reduced [HFrEF] and preserved [HFpEF] ejection fraction, in a large cohort of US veterans. Methods: The study cohort included 401,348 Million Veteran Program participants with complete alcohol information collected through a survey and no HF at baseline. HF events were defined as 1 inpatient or 1 outpatient diagnosis code together with at least two ejection fraction (EF) measurements. We defined HFrEF as HF with left ventricular ejection fraction (LVEF) of ≤40% and HFpEF as heart failure with LVEF ≥ 50%. The associations between alcohol intake, type of beverage consumed (i.e., beer, wine, or liquor), and incidence of HF, HFpEF, and HFrEF were assessed using Cox proportional hazard models. Restricted cubic spline regression was used to assess for a dose–response association between alcohol consumption and the risk of HF. Results: Mean age was 65 years, and 91% were men. With a mean follow-up of 6.4 years, we observed 38,420 incident HF events (15,356 HFrEF, 19,047 HFpEF, and 4017 HF with an EF value of 41–49%). Compared to never drinkers, multivariable adjusted hazard ratios for HF were 0.90 (95% CI: 0.86, 0.94), 0.88 (95% CI: 0.84, 0.93), 0.86 (95% CI: 0.81, 0.91), 0.92 (95% CI: 0.86, 0.98), 0.95 (95% CI: 0.84, 1.06), and 1.08 (95% CI: 1.01, 1.15) for current drinkers of 0.1–0.5, 0.6–1, 1.1–2, 2.1–3, 3.1–4 drinks/day, and heavy drinkers (i.e., >4 drinks/day and/or those diagnosed with alcohol use disorder), respectively. We found a similar association between alcohol intake and risk of HFpEF and HFrEF, except heavy drinking was significantly associated with HFrEF (HR: 1.13, 95% CI: 1.02, 1.24), not HFpEF (HR: 1.05, 95% CI: 0.96, 1.13). Types of alcoholic beverage preference did not influence the alcohol-HF relation. Conclusions: Our data are consistent with a J-shaped relation between alcohol consumption and risk of heart failure, irrespective of subtypes. |

    2. Slatemanforlife on

      So … is 4 a day a lot? Cus, based on my experience, I’d estimate that at least a third of the barracks was at 4 drinks within the first hour of a Wednesday night barracks party.

    3. JoeyJoeJoeSenior on

      Alcohol is going to turn out to be just as bad as cigarettes.  There are so many early deaths from chronic use that we don’t even count because it’s hard to link them specifically to alcohol.  And nobody wants to know the truth because they love drinking.

    4. Binji_the_dog on

      Well it’s a good thing I only drink 3 40s a day. 

      On an unrelated note, my chest has kind of been aching a bit lately.

    5. JustaP-haze on

      What about 15-20 drinks about once a month?

      That’s less than 1/day… Right?

    7. mime454 on

      Wow so in this study up to 3 drinks per day was protective against heart failure compared to not drinking?

      I wonder if veterans who don’t drink are a very special subgroup. Former addicts? Very sick?

    9. WhyIsItAlwaysADP on

      1.25 drinks per day is optimal? My don’t drink 6 days a week and have 9 drinks on Saturday strategy is really paying off.

    11. linkton on

      4 per day is pretty much alkie territory. Chart seems to say most should be drinking more and that even moderate use isn’t bad for this.

    12. phalencrow on

      Thankyou for posting the paper not some pop science article. Very interesting.

    13. AwkwardTickler on

      Wait till climate change scarcity leads to people learning to brew and also over consume in mass while medication shortages ravage the world.

    14. Shoe-Logical on

      When I was in the army I easily drank 4+ a day, now I only drink some weekends. Maybe it is stress that is bad for your heart that is killing veterans/ service members?

    15. AnybodySeeMyKeys on

      So my average consumption of 1 snort a day is actually good for me?

    16. Pyrhan on

      Wohoo, another questionnable study in a predatory journal!

      So, for starters, their graphs only show the spline regressions, not the actual data points those regressions are based on?

      And those data points are supposedly reported in their tables, but **that doesn’t seem to match the regressions on the graphs???**

      For instance, table 2 shows the heart failure hazard ratios for the „3.1-4 drinks/day“ group is still well below that of either never drinkers or former drinkers, yet the hazard ratio curve in figure 1 crosses the line between 3 and 4 drinks per day?

      Or am I completely misunderstanding something here?

      In addition to this:

      >Participants who did not report any alcohol intake during the prior years or “never or less than once per month” for all three alcohol categories (i.e., wine, beer, and liquor) or responded “No, I have never drunk alcohol” to the question about whether they drank alcohol were categorized as “Never drinkers.” Those who responded “No, but I used to drink alcohol” were categorized as “Former drinkers.” Those who responded, “Yes, I currently drink alcohol”, were considered current drinkers, and subsequent questions were used to calculate drinks/day for categorization in the intake.

      I think it’s pretty safe to assume the „former drinkers“ group is probably going to include a significant number of recovering alcoholics, and other people who can’t consume alcohol due to medical conditions.

      Which would explain why, in tables 2, 3 and 4, „former drinkers“ are consistently at a higher risk than **both** former drinkers and current drinkers.

      > we assigned the median value within each group (zero for **both never and former drinkers**) and modeled this variable continuously.

      So, this would mean that they have completely skewed the „zero drinks per day“ point on their curves. (Especially since there are much more „former drinkers“ than „never drinkers“ in their groups.)

      It would also make the regression on their graphs even more irreconciliable with the data reported in their tables.

      Also, I find it rather surprising that „never drinkers“ at a **higher** risk of heart attack than essentially everyone except full-on alcoholics (>4 drinks per day) and former drinkers.

      Maybe it is a genuine protecting effect of alcohol. Or maybe a small portion of „former drinkers“ misread the questionnaire and ticked the wrong box… (I don’t think it would take many to get that result)

      Seriously, this sub should ban articles from well-known predatory publishers like MDPI. If that research was worth anything, it would be published somewhere better.

    18. Dizzy_Slip on

      The J shaped curve of alcohol consumption is quite probably related to lifestyle choices. People who drink moderately are more likely to be health conscious and therefore engage in other positive lifestyle choices like eating a proper diet and exercise.

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