Eine einzelne Darmmikrobe verhindert eine Gewichtszunahme und verhindert eine Fettzunahme, selbst bei einer fettreichen Ernährung. In einer neuen Studie stellten Mäuse, denen eine fettreiche Diät und zusätzlich Turicibacter verabreicht wurden, im Vergleich zu einer Kontrollgruppe einen verringerten Blutzuckerspiegel, geringere Fettwerte im Blut und eine geringere Gesamtgewichtszunahme fest.
https://newatlas.com/diet-nutrition/weight-gain-gut-microbe/
17 Kommentare
I’ve linked to the news release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:
https://www.sciencedirect.com/science/article/pii/S1550413125004413
From the linked article:
**Weight gain single-handedly prevented by a gut microbe**
Researchers have homed in on **a single gut microbe that acts to prevent fat gain, even with a high-fat diet**. The discovery adds to the booming science of finding ways to enlist the microbes that already live in our bodies to help us improve our health.
**In their study, mice that were fed a high-fat diet and were also given Turicibacter saw reduced blood sugar, lower levels of fat in the blood, and less overall weight gain compared to a control group.**
Is this in some ways the modern equivalent of the tapeworm diet?
I mean whatever works at the end of the day, but I always wonder how this will work long term – if it helps inhibit overeating it’s own thing but if it’s have your cake and the bacteria eat it. I wonder how that will go with humans vs mice.
“Even with a high fat diet”? Is there any evidence that high-fat diets are linked to weight gain? I was under the impression that this theory was a debunked industrial psyop by the sugar industry to deflect attention from how radically unhealthy their product is.
An interesting aspect from the summary:
>Human metagenomic analysis demonstrates reduced *Turicibacter* abundance in individuals with obesity. Similarly, a high-fat diet reduces *Turicibacter* colonization, preventing its weight-suppressive effects, which can be overcome with continuous *Turicibacter* supplementation. Ceramides accumulate during a high-fat diet and promote weight gain. Transcriptomics and lipidomics reveal that the spore-forming community and *Turicibacter* suppress host ceramides. *Turicibacter* produces unique lipids, which are reduced during a high-fat diet. These lipids can be transferred to host epithelial cells, reduce ceramide production, and decrease fat uptake.
This supports my non-scientific hypothesis that some individuals can eat nearly anything they want and not gain as much as others. Glad we’re getting a better understanding of this.
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How about with a high suger diet?
I worry that this would lead to gallstones. Wonder if they studied that.
I’ve seen enough, give me the bug.
To save anyone time from looking…. very unfortunately the answer is NO, this bacteria is not available in any online probiotics, medications, foods, or anything else. It is a rare isolated bacteria not available to buy anywhere.
Do we have an understanding of where particular strains of bacteria in our gut microbiome come from?
It says that concentrations of this bacteria are suppressed by obesity, but could it just be that obese people are likely to have diets which include less of wherever this bacteria comes from? Or is it not that simple?
Is our microbiome composition informed in some way by the circumstances of our birth, or where we live, or genetics providing an environment suitable for some but not others?
„even with a high-fat diet“ as if that is the cause of weight gain
Im gonna sprinkle this one my milkshakes
Doesn’t a standalone high fat (keto) diet render the same results? Many people report so
The big issue I see missing from most of the discussions with these types of breakthroughs is like the history of finding vehicle energy alternatives, big oil has a brutal history of taking these out of the market and destroying them. Big Pharma, big food, big healthcare, etc…many powerful industries have a VERY BIG vested interest in keeping these types of breakthroughs from ever becoming available……and this is precisely why scientific research such as this MUST be publicly funded so that it DOES become accessible to benefit people ASAP to save lives!!!
Ah that’s cool, can’t wait to never hear of this again.
Interesting. I started gaining weight super fast after taking Doxycycline for Lyme disease. I was the same weight for years, but gained about 12 lbs in the last about 4 months and it’s still going up. I even cut back on calories and upped my exercise. Nothing seems to stop the constant gain. Never had any sort of issue prior to the Doxycycline.
I wonder if it killed off the Turicibacter and other beneficial bacteria in my gut.
Promising, but important to keep perspective: this is a mouse study. Gut microbes clearly influence metabolism, but translating a single strain into safe, effective human treatments is a long road. Fascinating mechanism, though.