Eine langfristige Kalorieneinschränkung kann die biologische Alterung des Gehirns verlangsamen. Die Forschung liefert Beweise dafür, dass eine Reduzierung der Kalorien um 30 % die Stoffwechselfunktion der Zellen erhält, die für die Isolierung der Nervenfasern verantwortlich sind.

>A new study suggests that restricting calorie intake over a lifetime may slow the biological aging of support cells in the primate brain. The research provides evidence that a thirty percent reduction in calories preserves the metabolic function of cells responsible for insulating nerve fibers. These findings were published in the journal Aging Cell.

>The brain relies on complex networks of communication to function correctly. This communication depends heavily on white matter, which consists of nerve fibers coated in a protective fatty substance called myelin. As primates age, this white matter tends to degrade. The loss of integrity in these areas often correlates with cognitive decline and slower processing speeds.

>Scientists have sought to understand the cellular mechanisms that drive this age-related deterioration. Much of the focus has shifted toward glial cells, which were once considered merely supportive glue for neurons. It is now understood that glial cells, specifically oligodendrocytes and microglia, actively maintain brain health. Oligodendrocytes produce myelin, while microglia act as the brain’s immune system.

>When these cells malfunction due to aging, they may contribute to the breakdown of white matter. Previous research in rodents has indicated that reducing calorie intake can extend lifespan and delay age-related diseases. However, it remains less clear how such interventions affect the complex brains of higher primates.

>To investigate this, a team of researchers examined the effects of long-term calorie restriction on the rhesus monkey brain. The rhesus monkey serves as a robust model for human aging due to similarities in brain structure and cognitive decline patterns. The study utilized brain tissue from animals involved in a long-running project by the National Institute on [Aging](https://doi.org/10.1111/acel.70298).

Another day, more papers pushed along on r/science encouraging me to restrict calories, avoid alcohol, go plant-based, etc.

I’m not going to do any of that. I’d rather fully enjoy my life and die earlier.