Bluthochdruck wirkt sich viel früher als erwartet auf das Gehirn aus: „Die Veränderungen helfen zu erklären, warum Bluthochdruck ein Hauptrisikofaktor für die Entwicklung kognitiver Störungen wie vaskulärer kognitiver Beeinträchtigung und Alzheimer ist.“ »
https://news.weill.cornell.edu/news/2025/11/hypertension-affects-the-brain-much-earlier-than-expected
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« The extent of the early alterations induced by hypertension was quite surprising. Understanding how hypertension affects the brain at the cellular and molecular levels during the earliest stages of the disease may aid in developing therapeutic strategies to combat the progression of neurodegeneration in people with hypertension. »
Reference: Schaeffer, Samantha M. et al., Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution, Neuron, Online November 14, 2025. DOI: 10.1016/j.neuron.2025.10.018. https://www.cell.com/neuron/abstract/S0896-6273(25)00799-8
Is the same true for low blood pressure?
Well, add that to the compounding damaging effects of being an alcoholic smoker
Even though there are more veins than arteries in the brain, this hypertension correlation is for arteries and other blood vessels in the brain and not veins, right? I wonder at what point or trigger veins become the risk
> Early changes are driven by angiotensin II signaling, not elevated blood pressure
A relevant non-paywalled review from 2015: https://www.ahajournals.org/doi/10.1161/hypertensionaha.115.03624
And COVID. COVID also damages the brain in a frightening similar pattern to vascular dementia.