Erhitzter Tabak und Zigaretten verursachen die gleichen Darm- und Gefäßschäden. Sowohl HTPs als auch herkömmliche Zigaretten beeinträchtigen die Integrität der Darmbarriere und erhöhen das kardiovaskuläre Risiko, was Behauptungen über einen geringeren Schaden widerlegt. Die Ergebnisse unterstreichen die dringende Notwendigkeit strengerer Maßnahmen zur Tabakkontrolle

Implications for Tobacco Harm Reduction Claims
The findings demonstrate that both HTPs and cigarettes, whether actively used or passively inhaled, promote low-grade endotoxemia linked to oxidative stress and vascular impairment. This challenges industry claims that HTPs are meaningfully safer alternatives to traditional smoking.

Study Limitations and Public Health Implications
This study provides the first evidence connecting HTPs and cigarette exposure to elevated circulating LPS and zonulin in both children and adults, implying intestinal barrier dysfunction and cardiovascular risk. While comprehensive in scope, the study’s small sample size, lack of microbiome data, and absence of mechanistic experimentation limit the ability to draw causal conclusions. Prior cigarette use among HTP users could also confound results.

The authors further note that HTP aerosol temperatures can still reach levels sufficient for nicotine pyrolysis, potentially eliciting similar oxidative responses to those from combustible cigarettes. Nicotine exposure itself may exacerbate gut permeability and dysbiosis, amplifying oxidative stress.

Conclusion: 
Equal Risk from Heated and Conventional Tobacco
In conclusion, both HTPs and conventional cigarettes impair gut barrier integrity and increase cardiovascular risk, refuting claims of reduced harm. The results highlight the urgent need for stronger tobacco control policies and targeted public health interventions to protect both smokers and those exposed to second-hand smoke.

https://www.news-medical.net/news/20251103/Heated-tobacco-and-cigarettes-cause-the-same-gut-and-vascular-damage-study-finds.aspx

Go after exhaust and indoor pollution first if you care about health and not social control.