
Eine frühe Zuckerrestriktion ist mit einem geringeren Asthma- und COPD-Risiko bei Erwachsenen verbunden. Personen, die sowohl im Mutterleib als auch ein bis zwei Jahre nach der Geburt einer Zuckerrestriktion ausgesetzt waren, hatten ein um 25 % geringeres Risiko, an Asthma zu erkranken, und ein um 27 % geringeres Risiko, eine chronisch obstruktive Lungenerkrankung zu entwickeln
Early-life sugar restriction is linked to lower adult asthma and COPD risk, study finds
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The study utilized data from the UK Biobank, a large-scale biomedical database containing health information from over half a million participants. The researchers focused on 58,670 individuals born in the United Kingdom between 1951 and 1956. Based on their birth date, participants were categorized by their exposure to the national sugar rationing policy during their first 1,000 days of development. Those born before July 1954 were considered exposed to rationing for varying lengths of time, while those born after this date were considered unexposed.
The scientists then tracked the participants’ health records over many years to identify new cases of three respiratory diseases: asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. They also analyzed results from spirometry tests, which measure lung function. These tests assess metrics like the total amount of air a person can exhale and how quickly they can exhale it. The analysis accounted for a wide range of factors, including age, sex, socioeconomic status, smoking history, parental health, and other medical conditions.
The results showed a clear association between being exposed to sugar rationing in early life and better respiratory health in adulthood. Individuals who experienced sugar restriction both in the womb and for one to two years after birth had a 25% lower risk of developing asthma and a 27% lower risk of developing chronic obstructive pulmonary disease compared to those who were not exposed to rationing.
https://www.sciencedirect.com/science/article/pii/S0002916525005982?via%3Dihub
„our analysis is subject to right censoring, and we lack data on prestudy mortality; as a result, individuals who died before recruitment are not captured, which may introduce survivor bias“
Since we’re talking about a time period over 70 years years ago, this seems very important. What’s the life expectancy of people with the diseases studied?