Forscher haben den ersten pillengroßen Biodrucker vorgestellt, der geschluckt und in den Magen-Darm-Trakt geführt werden kann, wo er Biotinte direkt auf geschädigtem Gewebe ablagert, um die Reparatur zu unterstützen

>MEDS is designed like a ballpoint pen with a spring tip that releases ink — except here, the device is much smaller, and the ‘ink’ is a living bio-gel. About the size of a pill, MEDS contains a tiny chamber of bio-ink and a spring-plunger mechanism that pushes the material out. With no on-board electronics, the release is switched on by an external near-infrared laser beam that safely penetrates the body’s tissues. As the bio-ink emerges, the capsule is steered with precision by an external magnet mounted on a robotic arm, much like guiding a joystick.
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>In their experiments, the EPFL team used their bioprinter to repair artificial ulcers of various sizes on simulated gastric tissue, and even to seal a simulated hemorrhage. In in-vivo experiments performed at an accredited animal research facility in the US, the researchers also successfully used their device to deposit bio-ink in the gastric tracts of rabbits. In these experiments, the team tracked the capsule’s movements using x-ray fluoroscopy, demonstrating the potential of the device – which can be retrieved orally using magnet guidance – for minimally invasive repair.

[A Pill That Prints‐An Ingestible Bioprinter for Non‐Invasive Structured Bioink Deposition – Manoharan – Advanced Science – Wiley Online Library](https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202512411)