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    Vergessen ist eher ein aktiver Dopamin-Prozess als eine Gehirnstörung. Eine Studie mit Würmern, die zu 80 % genetisch mit Menschen identisch sind, zeigt, dass Dopamin sowohl bei der Gedächtniserhaltung als auch beim Vergessen hilft: Würmer, die nicht in der Lage sind, Dopamin zu produzieren, behalten ihr Gedächtnis deutlich länger als normale Würmer

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    1. nohup_me on

      >Published in the Journal of Neurochemistry, the study used tiny worms called Caenorhabditis elegans – one millimetre long with only 300 neurons, yet 80% genetically identical to humans – to explore how memories fade.
      >
      >These microscopic creatures might seem worlds apart from humans, but their brains share many of the same molecular pathways that makes them perfect for studying brain pathways including memory.

      >
      >Surprisingly, worms that could not produce dopamine held onto the memory much longer than normal worms. In other words, without dopamine, they took much longer to forget.
      >
      >Dr Chew explains, “We often think of forgetting as a failure, but it’s actually essential. If we remembered everything, our brains would be overwhelmed. Forgetting helps us stay focused and flexible.”

      > The team also discovered that two specific dopamine receptors—DOP-2 and DOP-3— which are similar to some dopamine receptors found in humans, work together to control forgetting. When both were disabled, the worms clung to their memories just like the dopamine-deficient ones.

      [Dopaminergic Modulation of Short‐Term Associative Memory in Caenorhabditis elegans – McMillen – 2025 – Journal of Neurochemistry – Wiley Online Library](https://onlinelibrary.wiley.com/doi/10.1111/jnc.70200)

    2. Glittering_Cow945 on

      forgetting _in worms with 300 neurons_ has to do with dopamine. extrapolation to humans is more than risky.

    3. agentobtuse on

      In an ADHD brain we gotta flood our brains with dopamine to focus in order to remember at times. Does this give evidence that ADHD brains are truly wired differently?

    5. cookiesphincter on

      Im more surprised to find out there are worms that are 80% genetically identical to humans.

    6. omnichronos on

      If so, I wonder why Parkinson’s patients demonstrate worse memory retention, given their lower dopamine.

    7. swimwithdafishies on

      This makes sense why emotionally charged memories are vivid and story like in our memory, while boring day to day work stuff can be hard to remember. Not much dopamine there.

    8. grapescherries on

      I wonder if there’s a link between this and rumination in depression and being unable to move on in grief. It also makes sense that happiness is what gets people/animals to move on.

    9. magus678 on

      I wonder at the implications here in understanding depression.

      It certainly makes sense to me, at least narratively, that the sense of being „stuck“ and constant rumination might both be related to this effect.

      A sort of „logjam“ that spends overlong at a particular snapshot simultaneously causing and caused by the inability to accept new inputs that should be moving the picture along.

    10. McCool303 on

      Hopefully this research goes further as someone with ADHD and FND I’m in a constant state of randomly forgetting things.

    11. AppropriateCase7622 on

      The ADHD ability to remember random stuff makes a lot more sense now

    12. Ilaxilil on

      Oh that must be why I remember my entire childhood and nothing else. Just haven’t felt joy since then.

    13. whatidoidobc on

      Wording it that way, as 80% genetically identical to humans, is going to be completely misleading to anyone that isn’t a geneticist. This is a great example of „selling“ your research in ethically questionable ways.

    14. caitbenn on

      I would love for someone more educated on this topic than me to comment on the potential connection between this finding and the study showing that people with ADHD and autism don’t prune as many neural pathways during development.

    15. sermer48 on

      Aren’t we 60% genetically identical to bananas? So this is a study of something halfway between humans and bananas…80% just seems really low.

    17. golden_ember on

      I wish that was the case for me – my memory is awful.

      I also can’t see anything in my mind if I try to close my eyes and picture stuff.

      I’d be more curious to know if there’s a link there or not.

      My memory is more muscle and emotionally based. I can’t “see” where to go in a software but I can tell you by thinking about what I would physically do to get there. Really big emotions, especially bad ones, I tend to remember more.

      But even then, my mom will talk about something that’s happened, someone I’ve dated, etc and I’m like, “huh?”

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