Mäuse, die mit der Keto -Diät gefüttert wurden, hatten Probleme mit der Verarbeitung von Zucker, zeigten Anzeichen einer Leber- und Herz -Kreislauf -Erkrankung | Langfristige Einhaltung des kohlenhydratarben, fettreichen Diäts verursachte Fettanbautungen im Blutkreislauf
12 Kommentare
How incredibly predictable. It’s like we had years of research that pointed to this already.
We knew this years ago… Hell, even foamy the squirrel knew this.
Not exactly a mouse expert, but I’d be curious to see the effects in a more omnivorous/carnivorous species…?
I’m pretty open to the evidence that a ketogenic diet has health benefits for a number of use cases. But I’d never go for it myself because I know I have a genetic predisposition for high cholesterol (that makes dietary cholesterol affect my levels), non-alcoholic fatty liver disease, cardiovascular risk, and kidney insufficiency. I don’t need evidence that it’s bad for other people before I know it’s bad for me personally.
There is a study showing that a ketogenic diet [extended longevity and healthspan in male mice](https://pmc.ncbi.nlm.nih.gov/articles/PMC5609489/). Scientific inquiry generates plenty of conflicting evidence. I hope we can look at this as a sign that, especially when it comes to medical science, your mileage is still highly individualised, and overall risk to health and longevity is a composite of the accumulated risks of many interconnected systems. I think it’s worth the investment to learn about your own biological composition to anchor your decisionmaking instead of looking for an „objective“ direction.
> Adult C57Bl/6J male and female mice were placed on one of four long-term diet regimens
[C57BL/6J is the most widely used inbred strain[…]They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis.](https://www.jax.org/strain/000664)
It’s good to know that feeding mice that have genetic predispositions to conditions, which naturally mostly eat seeds, grains and some insects, with extremely species inappropriate diets, leads to them having metabolic problems.
So their conclusion of:
> In summary, while a KD can prevent and treat obesity, it causes hyperlipidemia, hepatic steatosis, and glucose intolerance.
Should come with a big, red, bold
# IN MICE.
Good thing we’re not mice…
I’ve always said keto is a great weight loss “tool” but never thought of it as a long term method of sustaining weight loss.
Mice are not humans and I could not see which exact fats were used.
I only eat healthy fats such as grass fed butter, grass fed tallow, avocado, olive, walnut oil.
A 90% fat diet is not a modern keto diet. Generally 70% 25% 5% (fat, protein, carbs) is the most common. Also, different strains of mice have been known to respond dramatically different to keto diets. Also, they’re mice.
KD is bad for mice I guess?
It’s been 4 billion years ands we still haven’t found a diet that is good for us
Not surprised. Anyone who actually knows what’s up with keto uses different macro ratios.
1g/lb of body weight protein from high quality sources.
Minimal fat, just enough to be satiated. You want your body to use its fat stores, but not cannibalize muscle mass in the process.
Under 20g carbs, mostly from leafy greens.
Eat meat and leafy greens and avocados, it’s not rocket surgery.