Untersuchungen zeigen hohe Beatmungsanhauch – absichtlich schneller und tiefer einatmen, um die Sauerstoffaufnahme zu erhöhen und mehr CO2 auszuschließen -, während das Hören von Musik zu veränderten Bewusstseinszuständen führen kann, ähnlich denen, die von psychedelischen Substanzen hervorgerufen wurden

Breathwork while listening to music may induce a blissful state in practitioners, accompanied by changes in blood flow to emotion-processing brain regions, according to a study published August 27, 2025, in the open-access journal PLOS One by Amy Amla Kartar from the Colasanti Lab in the Department of Clinical Neuroscience at Brighton and Sussex Medical School, U.K., and colleagues. These changes occur even while the body’s stress response may be activated and are associated with reporting reduced negative emotions.

The popularity of breathwork as a therapeutic tool for psychological distress is rapidly expanding. Breathwork practices that increase ventilatory rate or depth, accompanied by music, can lead to altered states of consciousness (ASCs) similar to those evoked by psychedelic substances. High ventilation breathwork (HVB) might offer a non-pharmacological alternative, with fewer legal and ethical restrictions to large-scale adoption in clinical treatment. However, the neurobiological mechanisms and subjective experience underlying ASCs induced by HVB have not been studied extensively.

To fill this knowledge gap, Kartar and colleagues characterized ASCs induced by HVB in experienced practitioners by analyzing self-reported data from 15 individuals who participated online, 8 individuals who participated in the lab, and 19 individuals who underwent magnetic resonance imaging. Their task consisted of a 20- to 30-minute session of cyclic breathing without pausing while listening to music, followed by a series of questionnaires within 30 minutes of finishing the breathwork session.

The results showed that the intensity of ASCs evoked by HVB was proportional to cardiovascular sympathetic activation, as indicated by a decrease in heart rate variability, indicating a potential stress response. In addition, HVB-evoked ASCs were associated with a profound decrease in blood flow to the left operculum and posterior insula – brain regions implicated in representing the internal state of the body, including breathing. Also, despite HVB causing large and global reductions in blood flow to the brain, there was a progressive increase in blood flow during the session to the right amygdala and anterior hippocampus, which are brain regions involved in the processing of emotional memories. These blood flow changes correlated with psychedelic experiences, demonstrating that these alterations may underlie the positive effects of this breathwork.

[https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0329411](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0329411)