Die Studie hat einen kritischen Hirn-Hub bei Mäusen abgebildet, das Stressreaktionen und soziales Verhalten reguliert und neue Beleuchtung auf die neuronalen Wurzeln psychiatrischer Erkrankungen wie posttraumatische Belastungsstörungen, Depressionen und Angstzustände abgibt
https://www.uclahealth.org/news/release/ucla-scientists-uncover-brain-network-controlling-stress-and
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>In his study, Dong’s team used advanced genetic labeling, 3D brain imaging and AI-driven circuit mapping to chart the intricate wiring of the medial prefrontal cortex (MPF or mPFC) in mice, including the dorsal peduncular area (DP) and infralimbic area (ILA). These regions act as hubs that integrate sensory and internal body signals to coordinate emotional and physiological responses. The findings reveal how these hubs govern emotional stability and stress regulation, offering a cellular-level blueprint of circuits that are conserved in the human vmPFC.
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>“Our work closes a critical gap in understanding how these brain regions orchestrate complex behaviors and stress responses,” said Dong. “By identifying the precise circuits involved, we open the door to developing better diagnostic tools and targeted therapies for psychiatric and neurological disorders.”
[Neural networks of the mouse visceromotor cortex | Nature](https://www.nature.com/articles/s41586-025-09360-w)