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    1. A new experimental obesity pill called SANA, developed by Eolo Pharma, shows promise as an alternative to GLP-1 drugs like Ozempic. Unlike GLP-1s which comes with gastrointestinal side effects and reduced appetite, SANA works by activating creatine-dependent thermogenesis which is a process that burns fat by generating heat in fat cells without affecting appetite. In a Phase I trial described in the journal Nature Metabolism, the drug led to statistically significant weight loss in participants after two weeks.

    2. The_Roshallock on

      I’m sure that a lot of testing is done for the efficacy and safety of these medications. This being said I still have a lot of reservations about medications that drastically affect a person’s metabolism. There is a lot that could go wrong with something like this if it doesn’t work exactly as expected.

    3. This is an interesting idea. But if you’re eating a shit load all day you probably should just be reducing your appetite regardless.

      I’m not sure why glucomannan isn’t more popular. You just add it to a shake, it expands in your stomach, you feel full. Problem solved.

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