Die Aufnahme gesättigter Fettsäuren erhöht das Risiko für mehrere Krebsarten
https://www.mims.com/philippines/news-updates/topic/saturated-fat-intake-ups-risk-of-several-cancers
Die Aufnahme gesättigter Fettsäuren erhöht das Risiko für mehrere Krebsarten
https://www.mims.com/philippines/news-updates/topic/saturated-fat-intake-ups-risk-of-several-cancers
4 Kommentare
„Individuals with high intakes of total and saturated fats are at increased risks of several cancers, according to a study. On the other hand, polyunsaturated fat intake appears protective.
A team of investigators searched PubMed, Embase, Web of Science, and the Cochrane Library from inception through September 2025 for systematic reviews and meta-analyses of observational or interventional studies assessing dietary fat intakes in relation to cancer incidence. They assessed the quality of methodology using AMSTAR-2 and evaluated evidence certainty with GRADE.
Twenty-three systematic reviews and meta-analyses met the eligibility criteria.
Higher intake of total fat correlated with elevated risks of bladder (relative risk \[RR\], 1.28, 95 percent confidence interval \[CI\], 1.04‒1.58), breast (RR, 1.10, 95 percent CI, 1.05‒1.16), gastric (RR, 1.18, 95 percent CI, 1.00‒1.39), and esophageal cancer (RR, 1.31, 95 percent CI, 1.13‒1.49) and non-Hodgkin lymphoma (RR, 1.26, 95 percent CI, 1.12‒1.42).
Saturated fatty acid intake also correlated with increased risks of breast (RR, 1.10, 95 percent CI, 1.03‒1.17), gastric (RR, 1.31, 95 percent CI, 1.09‒1.58), liver (RR, 1.34, 95 percent CI, 1.06‒1.69), and esophageal cancer (RR, 1.88, 95 percent CI, 1.28‒2.77).
Furthermore, monounsaturated fatty acid intakes showed a positive association with esophageal (RR, 1.70, 95 percent CI, 1.01‒2.84) and breast cancer (RR, 1.08, 95 percent CI, 1.01‒1.16) but an inverse association with skin cancer (RR, 0.90, 95 percent CI, 0.85‒0.96). Notably, polyunsaturated fatty acid intake appeared to protect against gastric cancer (RR, 0.77, 95 percent CI, 0.65‒0.92).
“Dietary fats may influence carcinogenesis through pathways involving lipid metabolism, oxidative stress, and inflammation,” the investigators said.
[_Am J Clin Nutr_](https://ajcn.nutrition.org/article/S0002-9165(26)00075-4/abstract) 2026;123:101266″
This has been very well understood for a long time. It’s worth mentioning too though that these associations with “oxidative stress” can also be due to genetic factors. For instance, I’m borderline underweight, have under 10g of saturated fat per day, lost 25 pounds in a year and a half, am plant-based, and still have some weird ass blood sugar readings and swings with finger pricks. I also have pretty abysmal total cholesterol numbers (though I haven’t had that tested since before I lost weight and watched my satty fatties).
Keep chugging down those cheeseburgers trumpy
Salt, sugar and fat are the keys to keeping people addicted to foods and all of them come with consequences. Saturated fat – despite what RFK may proselytize – is clearly something to be avoided whenever possible.