Globale DNA-Studie: Wo Sie leben, kann sich darauf auswirken, wie schnell Sie altern. Der ethnische Hintergrund hinterlässt tiefe Spuren in Ihrem Immunsystem, Ihrem Stoffwechsel und Ihren Darmbakterien, egal wohin Sie ziehen: Ostasiaten außerhalb Asiens waren biologisch älter als diejenigen in Asien, Europäer zeigten das entgegengesetzte Muster
https://www.manchester.ac.uk/about/news/world-first-dna-study-where-you-live-may-change-how-fast-you-age/
9 Kommentare
>Genetic ancestry refers to the estimation of where your ancestors came from based on patterns in your DNA, inherited across generations.
>
>They found that your ethnic background leaves a deep mark on your immune system, metabolism and gut bacteria no matter where you move.
>
>South Asian volunteers showed signs of higher exposure to pathogens across multiple biological layers.
>
>European participants had richer gut microbial diversity and higher levels of chemicals tied to heart disease risk.
>
>But geography also rewired key molecular networks involved in cholesterol, inflammation and energy processing.
>
>Moving continents was enough to shift major metabolic pathways and alter the balance of gut microbes.
>
>The most dramatic finding was that geography appears to change biological age — the molecular measure of how old your cells look.
>
>East Asians living outside Asia were biologically older than those who stayed in Asia.
>
>Europeans showed the opposite pattern, appearing biologically younger when living outside Europe.
>The study also uncovered a never-before-seen link between a telomerase gene involved in cellular ageing and a specific gut microbe, connected through a lipid molecule called sphingomyelin.
>
>This unexpected three-way link hints at a molecular chain reaction through which gut bacteria may influence how quickly our cells age.
>
>The findings create a powerful new resource for precision medicine, highlighting the need for healthcare tailored to genetic ancestry and environment rather than a one-size-fits-all model.
[A comparison of deep multiomics profiles across ethnicity, geography, and age: Cell](https://www.cell.com/cell/fulltext/S0092-8674(26)00467-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867426004678%3Fshowall%3Dtrue)
Did the University of Manchester use AI imagery to illustrate their scientific finding? Yikes.
Yes if you experience less stress from racism you will age slower. And if your race is exalted you will age even slower still. Stress wrecks your DNA.
Probably indicative of cuisine & food availability instead of latitude/longitude.
The west has higher amounts of ultra processed foods and a higher cost to healthy foods.
This might be a micro / trivial comment: but in my own personal observations I have suspected this to be the case as to why everyone where I live (NYC) seems to visibly age faster than their peers who live in more rural (non agricultural) areas of the world. Pollution, etc. despite a lot living generally healthy lifestyles.
How does one effectively eliminate socio-economic factors that can play a big role in aging between these groups?
It’s naive to assume average European overseas would have the same living conditions as average East Asian.
So white Americans are biologically younger than Europeans? That’s surprising.
Why are East Asians biologically older outside Asia? Is it because of stress or diet?