„*Scientists at MIT may have found a key reason. A newly identified gene mutation appears to disrupt a brain circuit that helps us update our understanding of the world. When this system fails, the brain may cling to old ideas even when reality changes.*
*In experiments with mice, researchers showed that this mutation interferes with the brain’s ability to adjust decisions based on new input, a problem that closely mirrors cognitive symptoms seen in schizophrenia.*
*The mutation occurs in a gene called grin2a, previously linked to schizophrenia in large genetic studies. The findings suggest that targeting this circuit could eventually help improve cognitive function in some patients.*“
thegoldengoober on
Hopefully this leads to a rapid solution for humans. This is such a distressing and tragic condition. Of course, all degenerative brain conditions are.
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From the article:
„*Scientists at MIT may have found a key reason. A newly identified gene mutation appears to disrupt a brain circuit that helps us update our understanding of the world. When this system fails, the brain may cling to old ideas even when reality changes.*
*In experiments with mice, researchers showed that this mutation interferes with the brain’s ability to adjust decisions based on new input, a problem that closely mirrors cognitive symptoms seen in schizophrenia.*
*The mutation occurs in a gene called grin2a, previously linked to schizophrenia in large genetic studies. The findings suggest that targeting this circuit could eventually help improve cognitive function in some patients.*“
Hopefully this leads to a rapid solution for humans. This is such a distressing and tragic condition. Of course, all degenerative brain conditions are.