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15 Kommentare
>It was all smooth sailing, in fact, until the researchers started cloning their 25th through 27th generations of mice. But by the 58th generation, according to Wakayama’s team, the mice did not even survive for more than a day.
Reference: Wakayama, S., Ito, D., Inoue, R. et al. Limitations of serial cloning in mammals. Nat Commun 17, 2495 (2026). https://doi.org/10.1038/s41467-026-69765-7
[deleted]
Kind of funny that the movie Multiplicity got this right. It was a major plot point that the main character’s clone clones himself and it doesn’t quite work out right.
Coulda told you this from
Weed cultivation.
So the difference between this and asexual reproduction is scale? ie, mutations happen and only survivable mutations survive?
Inbreeding. Right, y’all?
What about marbled crayfish? They seem to be doing great (unfortunately).
The asgard did this but unfortunately ended up blowing up their own world because they couldn’t solve the problem. It seems like a good idea in concept. Animals have been making copies since forever with albeit slight changes over time.
If you save enough generic material from the original, could you just keep cloning the original instead of needing to clone generation after generation of clones and having it deteriorate?
the same has been observed with Model Collapse in LLMs, seeing as that is largely just duplication of duplicated information.
Not surprising, the Asgard already knew this.
Someone’s Never used a Copier before, huh?
How does sexual reproduction differ? If the zygote was cloned early enough in its lifecycle does that change things?
That’s what happens when you VHS a VHS…