Psilocybin setzt eine spezifische biologische Signatur im Gehirn frei, die mit tiefgreifenden mystischen Zuständen verbunden ist. Wissenschaftler fanden heraus, dass diese messbaren Veränderungen der Gehirnwellen direkt mit der Intensität der psychedelischen Erfahrung einer Person korrespondieren.

Link to actual study

[https://www.sciencedirect.com/science/article/pii/S0278584626000229?via%3Dihub](https://www.sciencedirect.com/science/article/pii/S0278584626000229?via%3Dihub)

# Highlights

* • Psilocybin reduced theta/alpha and increased beta/gamma power compared to placebo.
* • EEG changes were correlated with subjective psychedelic experiences.
* • Psilocybin enhanced beta/gamma connectivity in DMN and parietal regions.
* • Baseline EEG predicted subjective effects, indicating potential for stratification.

# Conclusions

Psilocybin induces significant changes in brain function, characterized by altered EEG power and connectivity. These changes correlate strongly with subjective experiences, supporting psilocybin’s potential for treating mental disorders. The predictive value of baseline EEG features for subjective alterations suggests that specific brain activity patterns may serve as biomarkers for tailoring psilocybin therapy in clinical settings. This study enhances our understanding of psilocybin’s neurophysiological impacts and informs future therapeutic applications.

Personally, mushrooms helped lift me from my trauma brain and negative cycles. I was so focused on healing from the past, I forgot the path was the present with presence. First time I felt gratitude. I kept at it with microdoses and long walks. A great way to confront the self. It’s truly a great way to reprogram yourself from your own internal narritives