
Eine neue Studie zeigt, dass höhere Buprenorphin-Dosen Patienten dabei helfen, die Behandlung von Opioidkonsumstörungen fortzusetzen
https://theconversation.com/higher-buprenorphine-doses-help-patients-stay-in-opioid-use-disorder-treatment-new-study-finds-274804
Ein Kommentar
From the article:
Buprenorphine is one of the most effective treatments for opioid use disorder. Unlike most opioids, buprenorphine only partially activates opioid receptors, providing enough stimulation to prevent withdrawal and cravings while not causing euphoria. This lowers the risk of overdose.
Buprenorphine also blocks other opioids from binding to opioid receptors and causing euphoric effects. This deters patients from using other opioids while on the medication.
Across the board, patients who received higher doses of buprenorphine – usually 17 to 24 milligrams per day, but sometimes more – stayed in treatment significantly longer than those who started on medium doses of 9 to 16 milligrams, or lower doses of 8 milligrams.
Staying in treatment for opioid use disorder is important because it reduces overdose risk and provides a foundation for recovery.
Peer-reviewed paper is open access:
Buprenorphine dosing patterns and treatment outcomes for patients with opioid use disorder insured by Medicaid in Philadelphia. French, Rachel et al. *Journal of Substance Use & Addiction Treatment,* Volume 183, 209879.
https://doi.org/10.1016/j.josat.2025.209879