Mikroben, die Erdnussallergieproteine ​​„entwaffnen“, wurden in Mund und Darm entdeckt. Experimente an Mäusen zeigten, wie Rothia und Staphylococcus Ara h 1 und 2 abbauen können, wodurch möglicherweise die Menge an Auslösern verringert wird, auf die das Immunsystem reagieren muss.

>Bacteria that live in our mouths and intestines can ‚disarm‘ the proteins that trigger allergic reactions to peanuts, a new study has found.

>Giving people with severe peanut allergies a hefty boost of these microbes could potentially help them cope better with exposure – but that’s still a long way off.

>A [team](https://www.sciencedirect.com/science/article/abs/pii/S1931312826000818?via%3Dihub) led by scientists from the Autonomous University of Madrid in Spain and McMaster University in Canada has identified two microbes – Rothia and Staphylococcus – with this unique ability.

>These bacteria, which occur naturally in human saliva and the small intestine, can break down the proteins in peanuts that trigger life-threatening anaphylaxis.

>This serious allergic reaction is the reason schools elect to outlaw peanuts: while up to 2 percent of people in Europe and the US have peanut allergies, rates are much higher among children, for whom the risk of death is far greater, too.

>Allergic reactions happen when our bodies identify a threat, but anaphylaxis to peanuts is something of an overreaction, a glitch in the immune system.

>The danger a peanut actually poses to the body (mainly, that our own digestive enzymes can’t break it down properly) pales in comparison to the danger of an anaphylactic response.

>People with severe peanut allergies produce large amounts of immunoglobulin E (IgE) antibodies when exposed to peanut proteins, including two called Ara h 1 and 2. This leads to an inflammation response strong enough to cause their throat to swell shut and blood pressure to drop, in a reaction called anaphylactic shock.