Wissenschaftler waren begeistert von einem Nasenspray-Impfstoff gegen die Vogelgrippe, der bei Nagetieren eine „starke Immunantwort“ hervorrief. Bei herkömmlichen Grippeimpfstoffen durch Injektion liegt die Wahrscheinlichkeit, dass sich die geimpfte Person infiziert und das Grippevirus weitergibt, bei 40–60 %. Nasenimpfstoffe verhindern die Ausbreitung des Virus und verhindern die Übertragung.

Why scientists are so excited about a nasal spray vaccine for bird flu

The spray, administered in each nostril, generated a ‘strong immune response’ in rodents during an early-stage trial

While traditional flu vaccines, delivered by injection, are highly effective at preventing serious illness, there is still between a 40 and 60 per cent chance that a vaccinated person can become infected and silently pass the flu virus on to others.

Nasal vaccines, however, stop a virus from establishing itself in the nose and lungs – the sites where flu viruses first infect and replicate – meaning they also prevent onward transmission.

For those interested, here’s the link to the peer reviewed journal article:

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00655-X