Fast alle aufgeführten Nebenwirkungen von Statinen werden laut der umfassendsten Übersicht der Welt nicht durch Statine verursacht. Abgesehen von Muskelschmerzen und Diabetes sind nur 4 der 66 aufgeführten Nebenwirkungen – Veränderungen der Leberwerte, geringfügige Leberanomalien, Urinveränderungen und Gewebeschwellungen – nachweislich belegt.

https://www.theguardian.com/society/2026/feb/05/majority-statins-side-effects-not-caused-by-drug

7 Kommentare

  1. **Almost all side-effects listed for statins are not caused by the drugs, according to the world’s most comprehensive review of evidence.**

    **Other than the well-known risks around muscle pain and diabetes, only four of 66 other statin side-effects listed on labels – liver test changes, minor liver abnormalities, urine changes and tissue swelling – are supported by evidence**. And the risks are very small, according to the systematic review and meta-analysis published in the Lancet.

    Statins have been used by hundreds of millions of people worldwide over the last three decades and are proven to reduce heart attacks, strokes and cardiovascular deaths. At the same time, millions have been put off the drugs amid long-running safety concerns, with statin labels listing dozens of possible side-effects.

    The study is the most comprehensive assessment of evidence for listed side-effects of statins. It examined 19 randomised controlled trials involving 124,000 people, with an average follow-up of four and a half years.

    Of the 66 side-effects currently listed on product labels, researchers found no strong evidence to support statins causing 62 of them, such as memory problems, depression, sleep disturbances and nerve damage leading to tingling in the hands and feet.

    The results showed the risk of most listed side-effects was minimal while the benefits far outweighed potential harms. As a result, labels should be updated to better reflect the evidence so patients and doctors could make more informed choices about statins, the researchers said.

    For those interested, here’s the link to the peer reviewed journal article:

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01578-8/fulltext

  2. xenonrealitycolor on

    so, indirect causes are not allowed to be used as side effect causes for the medications. Like muscle pain causing a lack of exercise & diabetes becoming one that increases the risk of depression, sleep disturbances, nerve damage (directly a problem with that diabetus stuff), memory issues…..

    no, this is a terrible study that wants to conclude that direct side effects have no effects outside of those side effects which we know isn’t the case at all.

  3. Kindly_Resolve_2284 on

    yeah, that tracks with what I’ve seen. Statins get a bad rep online because of all the scary side-effect lists, but the actual evidence shows most of them aren’t really caused by the drug. Muscle pain and a slight risk of diabetes are the main real ones, and a handful of minor lab changes like liver tests or mild swelling. Everything else is mostly anecdotal or coincidental, it’s wild how much misinformation sticks, honestly. People see a long list and assume it’s all true, but studies with huge sample sizes tell a very different story

  4. Being a natural skeptic the first question I’d have is who funded the study? This sounds like news the pharmaceuticals would be the happiest and most incentivized to see. Yes, I know the funding sources are listed in the study, but those are usually „foundations“ and „councils“ and you’d have to then find out where those orgs get their funding.

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