Weltweite Sicherheitsdaten deuten darauf hin, dass schwere körperliche Komplikationen durch Psychedelika selten sind. Die Studie kommt zu dem Schluss, dass die hohen Raten des gemeldeten Drogenmissbrauchs im Zusammenhang mit diesen Drogen möglicherweise stark durch den gleichzeitigen Konsum anderer Rauschmittel und nicht nur durch den Konsum von Psychedelika allein beeinflusst werden.
Global safety data suggests severe physical complications from psychedelics are rare
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>A new analysis of global pharmacovigilance data indicates that while reports of psychiatric distress are common among users of classic psychedelics and MDMA, severe physical health complications appear to be relatively rare in real-world settings. The study [suggests](https://doi.org/10.1016/j.psychres.2025.116929) that the high rates of reported substance abuse associated with these drugs may be heavily influenced by the simultaneous consumption of other intoxicants rather than the psychedelics alone. These findings were published in Psychiatry Research.
>The consumption of psychedelic substances has increased significantly in recent years. This rise has occurred in both clinical settings, where researchers are testing these compounds for therapeutic potential, and in unregulated recreational environments.
>National surveys in the United States have documented a steady growth in the use of LSD and other hallucinogens among adults over the last two decades. While clinical trials generally indicate that these substances have a favorable safety profile, such studies are conducted under strictly controlled conditions with carefully screened participants.
>Clinical trials often exclude individuals with complex medical or psychiatric histories to ensure safety and data clarity. This exclusion criteria means that data from trials may not fully represent the risks faced by the general population using these drugs in naturalistic settings. There has been a lack of empirical research exploring the safety of psychedelic use within real-world samples.
>“Psychedelic use, mainly surrounding magic mushrooms (or psilocybin) and LSD, has been rapidly increasing within both recreational and academic contexts over recent years. Nevertheless, these substances may still carry some stigma and misconceptions surrounding their safety in the eyes of the public, and there has not been much research on the side effects related to real-world use of these substances,” said study author Omer A. Syed, a PhD student at the University of Toronto.
It’s not a binary solution of safe/not safe. They’re relatively safe when used properly and in a good setting. There is data on how to do this. They’re relatively risky when used carelessly. There are risk factors and combinations that increase the likelihood of an issue. There is data on what those are..
The back and forth trying to come to a blanket statement about psychedelics is less productive than just offering up the data and information and letting people decide for themselves.
I’d imagine part of the association is because once one learns that they were lied to about the dangers of psychedelics it makes one wonder if anti drug messages about hard drugs are also exaggerated.