Wissenschaftler finden einen Weg, das Sehvermögen bei Erwachsenen mit Sehschwäche „neu zu starten“ | Eine neue Mausstudie zeigt, dass eine kurzzeitige und reversible Betäubung der Netzhaut des amblyopen Auges für nur wenige Tage die visuellen Reaktionen des Gehirns auf dieses Auge wiederherstellen kann, selbst bei Erwachsenen.

    https://newatlas.com/medical/reboot-vision-adults-lazy-eye/

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    6 Kommentare

    1. No-Explanation-46 on

      >When one eye is deprived of vision early in life, it can lead to amblyopia, a condition more commonly known as lazy eye. This happens because a lack of input disrupts synapse formation in the brain’s primary visual cortex, weakening vision in that eye.

      >In 2016, researchers found that temporarily numbing both retinas could reverse vision loss from amblyopia, while a follow-up study in 2021 showed that numbing only the non-amblyopic eye could also improve vision in the weaker eye. This method is like the treatment used for children, which involves patching the healthy eye. These findings have been verified in adult animals of different species.

      >A new mouse study from neuroscientists at MIT’s Picower Institute [shows](https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01338-5) that briefly and reversibly anesthetizing the retina of the amblyopic eye for just a few days can restore the brain’s visual responses to that eye, even in adults. The results strengthen the idea that temporarily numbing a retina could help rebuild the weakened neural connections in an amblyopic eye.

      >“The amblyopic eye, which is not doing much, could be inactivated and ‚brought back to life‘ instead,“ says Picower Professor Mark Bear. „Still, I think that especially with any invasive treatment, it’s extremely important to confirm the results in higher species with visual systems closer to our own.“

    2. I wish all this research was conducted differently. That’s too many mice for every single research, it’s not that nice to do that

    3. My son has amblyopia. He’s not totally blind in that eye, but glasses only help minimally. This would be an awesome development if they could replicate it in humans!

    4. Similar to how people with RCPD (total inability to burp) are cured.

      The muscle responsible for burping is paralysed with Botox and it „resets“ it allowing the reflex to fire correctly.

      Theres a lot of potential in this area for treating certain neurological conditions imo.

    5. Octogenarian on

      When I was a kid, they had me wearing eye patches on my good eye to force my brain to use the bad one.  It didn’t work.  Why would anesthetizing the good eye make a difference?

      This feels like the same concept of eye patches.  

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