Jüngster LSD-Konsum mit geringerer Wahrscheinlichkeit einer Alkoholkonsumstörung verbunden | Dieser Befund steht im Gegensatz zum Konsum anderer psychedelischer Substanzen, bei denen im vergangenen Jahr kein ähnlicher protektiver Zusammenhang festgestellt wurde.

>Recent analysis of federal health data suggests that the recreational use of LSD is associated with a lower likelihood of alcohol use disorder. This finding stands in contrast to the use of other psychedelic substances, which did not show a similar protective link in the past year. The [results](https://www.tandfonline.com/doi/full/10.1080/02791072.2025.2583967) were published recently in the Journal of Psychoactive Drugs.

>Alcohol use disorder affects millions of adults and stands as one of the most persistent public health challenges in the United States. The condition involves a pattern of alcohol consumption that leads to clinically detectable distress or impairment. Individuals with this disorder often find themselves unable to control their intake despite knowing it causes physical or social harm. Standard treatments exist, but relapse rates remain high. Consequently, medical researchers are exploring alternative therapeutic avenues.

>In recent years, attention has shifted toward the potential utility of psychedelic compounds. Substances such as psilocybin and MDMA have shown promise in controlled clinical trials for treating various psychiatric conditions. However, there is a substantial distinction between administering a drug in a hospital with trained therapists and taking a drug recreationally. James M. Zech, a researcher at Florida State University, sought to investigate this difference. Zech collaborated with Jérémie Richard from Johns Hopkins School of Medicine and Grant M. Jones from Harvard University.

>The team aimed to determine if the therapeutic signals seen in small clinical trials would appear in the general population. They utilized data from the National Survey on Drug Use and Health. This government project recruits a representative group of American citizens to answer detailed questions about their lifestyle and health. The researchers pooled data collected from 2021 through 2023. The final dataset included responses from 139,524 adults.

>To ensure accuracy, the investigators did not simply look at who used drugs and who drank alcohol. They employed statistical models designed to account for confounding factors. They adjusted their calculations for variables such as age, biological sex, income, and education level. They also controlled for the use of other substances, including tobacco and cannabis. This process helped them isolate the specific relationship between psychedelics and alcohol problems.