Eine neue Studie an Personen mit ADHS ergab, dass Personen mit erhöhten Falten (Gyrifizierung) in den frontalen kortikalen Regionen des Gehirns im Allgemeinen besser auf die Behandlung ansprachen. Höhere Gyrifizierungsgrade sind im Allgemeinen mit einer erhöhten kognitiven Leistungsfähigkeit verbunden.

I’ve linked to the news release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:

https://www.nature.com/articles/s41398-025-03681-0

From the linked article:

An experimental **study of individuals with ADHD revealed that those with increased gyrification in frontal cortical regions of the brain generally responded better to treatment**. The treatment was either group psychotherapy or methylphenidate in combination with clinical management of symptoms.

However, neither group psychotherapy nor methylphenidate was more effective overall than the control conditions. The paper was published in Translational Psychiatry.

Cortical gyrification is the process by which the brain’s cerebral cortex **folds** into ridges (gyri) and grooves (sulci) during development, increasing its surface area without greatly expanding skull size.

These folds allow a much larger number of neurons and connections to fit within the limited space of the cranium. Gyrification begins prenatally and continues into early childhood as different brain regions mature at different rates.

**Higher degrees of gyrification are generally associated with increased cognitive capacity** because more cortical surface supports more complex neural processing.