Natürliche Verbindung verjüngt alternde Zellen in nur 28 Tagen: Urolithin A, ein Metabolit von Darmbakterien, der durch den Verzehr von Lebensmitteln wie Granatapfel und Walnüssen entsteht, kann das Immunsystem im mittleren Alter verjüngen und uns vor Zellschäden, Entzündungen und chronischen Krankheiten wie Krebs schützen.

I’ve linked to the news release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:

https://www.nature.com/articles/s43587-025-00996-x

From the linked article:

**Natural compound rejuvenates aging cells in just 28 days**

**Researchers have demonstrated how a secret weapon made in the gut, produced by consuming foods like pomegranate and walnuts, can rejuvenate the immune system in middle age, shielding us from cell damage, inflammation and chronic diseases including cancer**.

Researchers at Germany’s Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, have spent years investigating the metabolite urolithin A (UA), a natural compound that’s produced by gut bacteria in response to ingested ellagitannins from foods such as pomegranates, almonds, walnuts and some berries. The new study follows on from a breakthrough in 2022, when the team found that UA induced a biological pathway that rejuvenates the cellular power plants – mitochondria – in T cells, equipping these immune cells with more cancer-fighting might. But it goes far beyond cancer.

What they found was that UA safely rejuvenated the immune systems in several ways. It boosted the number of well-functioning CD8+ T cells (also known as cytotoxic T lymphocytes, or CTLs), which are important for fighting pathogens. These cells were found to have more peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), a protein that acts as the master controller of mitochondrial biogenesis – where cells generate new mitochondria. The participants receiving UA supplements also had lower oxidative stress in cells and a change in a number of inflammatory markers.

Essentially, UA triggered mitophagy, the process that recycles and renews the power source in cells, significantly increasing the number of young, naive T cells. It also improved the immune system’s ability to clear harmful bacteria.

Assuming you have to consume a crazy amount

https://en.wikipedia.org/wiki/Chiles_en_nogada to die for. The main ingredient is walnut and topped with pomegranate