Natürliches Molekül (NAD⁺) kehrt Gedächtnisverlust um, der bei der Alzheimer-Krankheit in Tiermodellen beobachtet wurde. In menschlichen Gehirnproben von AD-Patienten waren die EVA1C-Proteinspiegel deutlich reduziert, was die Fähigkeit von NAD⁺, das Gedächtnis/Verhalten im Hippocampus und im entorhinalen Kortex zu verbessern, untergrub.

I’ve linked to the news release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:

https://www.science.org/doi/10.1126/sciadv.ady9811

From the linked article:

**Natural molecule reverses memory loss seen in Alzheimer’s disease**

Boosting levels of a certain molecule that declines with age was found to restore memory and brain function in Alzheimer’s disease (AD) models – not just by improving energy metabolism, as previously thought, but by fixing RNA splicing errors that disrupt hundreds of genes crucial to neuron health.

Further testing found that silencing eva-1 in the worms and EVA1C in mice undermined the ability of NAD⁺ to correct splicing errors or improve memory/behavior. **In human brain samples from AD patients, the scientists found that EVA1C protein levels were significantly reduced in the hippocampus and entorhinal cortex – two regions of the brain linked to memory and early disease progression**.