Ältere Männer geben häufiger krankheitsverursachende Mutationen an ihre Kinder weiter
https://www.newscientist.com/article/2499225-selfish-sperm-see-older-fathers-pass-on-more-disease-causing-mutations/
Ältere Männer geben häufiger krankheitsverursachende Mutationen an ihre Kinder weiter
https://www.newscientist.com/article/2499225-selfish-sperm-see-older-fathers-pass-on-more-disease-causing-mutations/
14 Kommentare
The risk of older fathers passing on disease-causing mutations to their [children](https://www.newscientist.com/article-topic/children/) is higher than previously thought. Genome sequencing has revealed that among men in their early thirties, around 1 in 50 sperm have a disease-causing mutation – which rises to nearly 1 in 20 by the age of 70.
Journal reference: *Nature* [DOI: 10.1038/s41586-025-09448-3](https://doi.org/10.1038/s41586-025-09448-3)
Well that’s ruined my plans to take my time and not have kids until I’m 70.
So my kid could be Magneto?
More and more reasons for me to just not have kids i suppose.
Good thing everyone’s landing high paying jobs with lots of paternal leave right out of college so this won’t be a population level crisis.
Right?
I have heard of this before. Maybe a decade or so ago. I wonder if this is a rehash of previous studies.
Someone should let Robert De Niro know.
My second child has a mole/freckle right where I had skin cancer (I had it removed after she was born but had it before).
I always felt like it was a very odd coincidence and maybe it is but I always wondered if they were connected in some way. Not that this is proof but it’s interesting
it is insane that research is still pretty new, was questioning the fertility of men a taboo or soemthing? its not only age that has a influence of mens fertility but also lifestyle
alcohol, drugs,age, obesity and bad nutrition also have a negative effect on sperm quality but you dont see the same amount of fetility advice for men, men should at least abstain from alcohol while trying for a child and this isnt even a thing that gets talked about
[https://jheor.org/post/2235-new-research-points-to-dad-s-drinking-as-a-significant-factor-in-fetal-alcohol-syndrome](https://jheor.org/post/2235-new-research-points-to-dad-s-drinking-as-a-significant-factor-in-fetal-alcohol-syndrome)
Another reason to tell younger women in their 40s they should have younger partners to have kids with
Knew it. Better have kids under 27yo.
In the past (and to an extent today – looking at you Elon with your 100+ kids) males at the top of the social hierarchy would have hundreds of wives, concubines, slaves, harems etc, and would consequently have hundreds, sometimes *thousands* of children. Old dudes spamming out mutations from their grizzled old stale balls can produce good mutations too, and it’s theorized this was a driver in human evolution.
I’m older and already autistic. So, will my children be like super savant or something???
So what is the rate for 20-30 year olds?