Junk Food verdreht den Gedächtniszentrum des Gehirns und führt zu einem Risiko einer kognitiven Funktionsstörung: Innerhalb von nur 4 Tagen nach dem Verzehr fettreicher Diät mit fettem Junk-Food in Mausmodellen wird der Gedächtniszentrum des Gehirns gestört. Dies deutet darauf hin, dass Fett -Junk -Foods das Gehirn fast sofort vor einer Gewichtszunahme beeinflussen können.

I’ve linked to the press release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:

https://www.cell.com/neuron/abstract/S0896-6273(25)00622-1

From the linked article:

A new study from UNC School of Medicine researchers, published this week in Neuron, reveals a unique look at how **junk food rewires the brain’s memory hub – leading to risk of cognitive dysfunction**. This new research opens the door to early interventions that can prevent even long-term memory loss associated with obesity.

Led by UNC School of Medicine’s Juan Song, PhD, principal investigator, professor of pharmacology, and Taylor Landry, PhD, first author, Department of Pharmacology, researchers found that a special group of brain cells in the hippocampus, called CCK interneurons, become overly active after eating a high-fat diet (HFD), due to an impaired ability of the brain to receive glucose (sugar). This overactivity **disrupts how the hippocampus processes memory**, even after just a few days of high fat diet. This type of diet resembles typical Western-style junk food rich in saturated fat—like cheeseburgers and fries. The discovery also showed that a protein called PKM2, which controls how brain cells use energy, plays a key role in this problem.

Brain Health Study Summary

**Mouse models were placed on high-fat diet resembling fatty junk food** before starting behavioral testing.

**Within 4 days of eating high-fat diet, results showed CCK interneurons in the brain’s memory hub became abnormally active**.

**Results suggest fatty junk foods can affect the brain almost immediately, well before the onset of weight gain or diabetes**.