Neue Technik verwendet fokussierte Klangwellen und Hologramme, um Gehirnschaltungen bei lebenden Tieren zu kontrollieren

>Published in the journal Nature Biomedical Engineering online July 7, the current study featured experiments performed inside a living brain that accurately replicated how an activated neuron in one part of the brain can have far-reaching effects through connected circuits.
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>“Our work shows that activating entire sets of neural networks with transcranial ultrasound stimulation in a living mouse brain is possible,” said study co-senior author Shy Shoham, PhD. The other co-senior author is Daniel Razansky, PhD, at the University of Zurich and ETH Zurich in Switzerland.
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>“We also found that, by focusing on circuits of neurons that are distributed across brain regions rather than in any individual region, TUS leverages inter-connections within the circuits to make targeted neurons 10 times more sensitive to ultrasound,” said Dr. Shoham, who is codirector of the Tech4Health Institute at NYU Langone Health, and a professor in the Departments of Ophthalmology and Neuroscience at NYU Grossman School of Medicine. “This discovery potentially makes the technique more efficient, lowers the ultrasound power required, and could pave the way to safer transcranial ultrasound stimulation treatments in the future.”

> “Our findings provide new insights into how transcranial ultrasound stimulation activates circuits within a living organism,” said Dr. Shoham. “We hope the techniques and computational models we’ve developed will help other basic researchers probe the mechanisms of different brain circuits. Ultimately, our goal is to translate this work into transcranial ultrasound stimulation protocols to treat different human conditions, such as mental health disorders.”

[Holographic transcranial ultrasound neuromodulation enhances stimulation efficacy by cooperatively recruiting distributed brain circuits | Nature Biomedical Engineering](https://www.nature.com/articles/s41551-025-01449-x)