Experimentelle Arzneimittel umgekehrt Autismus -Symptome: Hyperaktivität im retikulären Thalamuskern, der mit Autismusverhalten verbunden ist. Medikamente, die diese Aktivität unterdrückten, kehrten autismusähnliche Symptome bei Mäusen um. Die Ergebnisse erklären Überlappungen zwischen Autismus und Epilepsie mit Potenzial für neue Therapien.
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I’ve linked to the news release in the post above. In this comment, for those interested, here’s the link to the peer reviewed journal article:
https://www.science.org/doi/10.1126/sciadv.adw4682
From the linked article:
**Experimental Drugs Reverse Autism Symptoms**
Summary: Researchers have identified hyperactivity in the reticular thalamic nucleus as a driver of autism-like behaviors in mice. This brain region, which gates sensory information, was found to be overactive during stimuli and social interactions, leading to seizures, repetitive behaviors, and social withdrawal.
By suppressing this activity with drugs, including one already under investigation for epilepsy, researchers were able to reverse these symptoms. The findings suggest a shared brain mechanism between autism and epilepsy and highlight a promising new target for treatment.
Key Facts
Brain Target: **Hyperactivity in the reticular thalamic nucleus linked to autism behaviors.*+
Treatment Success: **Drugs that suppressed this activity reversed autism-like symptoms in mice.**
Shared Pathways: **Findings explain overlap between autism and epilepsy, with potential for new therapies.**
As an autistic person, I wonder if it would also take away some of the positives that a lot of autistic people experience such as hyperfocus, stronger pattern recognition, good memory, etc.
If there ever were a „cure“ and it took away the obvious negatives like the sensory issues or difficulties with communication, but also took away my strengths, I’m not sure I’d be interested.
For more profoundly autistic people (level 2 or 3) I suspect the negatives far outweigh the positives so I’m not saying something like this wouldn’t help people.
What does autism in mice look like?!
If this solves sensory issues, my ASD1 daughter will be ecstatic. I’ve found her sobbing in her closet because she can’t stand the feeling of the clothes she wants to wear, and it breaks my heart.
Could this end with a vaccine to PREVENT autism? How the turntables.
thankfully I’m not a mouse
What does it even mean to be autistic as a mouse?