Forscher nutzen CRISPR, um die Kraft von Immunzellen gegen solide Tumore freizusetzen. In einer Mausstudie fanden Forscher heraus, dass sie mit CRISPR ein Gen namens FLI1 löschen können, um das Überleben menschlicher Killerzellen nach der Tumorinfiltration zu verbessern.

UCLA researchers use CRISPR to „unlock“ immune cells‘ power against solid tumors

In a mouse study, researchers found they can use CRISPR to delete a gene called FLI1 to enhance human killer cell survival after tumor infiltration

A UCLA-led research team has identified a genetic „brake“ that prevents the body’s natural defense system from attacking solid tumors. By using CRISPR technology to delete a specific gene called FLI1, researchers were able to significantly enhance the ability of Natural Killer (NK) cells to survive and inhibit solid tumor growth.

For those interested, here’s the link to the peer reviewed journal article:

https://www.cell.com/immunity/abstract/S1074-7613(26)00035-X